Age-Related Changes in Nucleus Pulposus Mesenchymal Stem Cells: An In Vitro Study in Rats

• Главные авторы: Yachao Zhao (Автор), Zhiwei Jia (Автор), Shanshan Huang (Автор), Yaohong Wu (Автор), Longgang Liu (Автор), Linghan Lin (Автор), Deli Wang (Автор), Qing He (Автор), Dike Ruan (Автор)
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• Опубликовано: Hindawi Limited, 2017-01-01T00:00:00Z.
• Предметы: article
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The functions of mesenchymal stem cells (MSCs) appear to decline with age due to cellular senescence, which could reduce the efficacy of MSCs-based therapies. Recently, MSCs have been identified in the nucleus pulposus, which offers great potential for intervertebral disc (IVD) repair. However, this...