Development and evaluation of natural gum-based extended release matrix tablets of two model drugs of different water solubilities by direct compression

• Главные авторы: Kwabena Ofori-Kwakye (Автор), Kwadwo Amanor Mfoafo (Автор), Samuel Lugrie Kipo (Автор), Noble Kuntworbe (Автор), Mariam El Boakye-Gyasi (Автор)
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• Опубликовано: Elsevier, 2016-01-01T00:00:00Z.
• Предметы: article
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The study was aimed at developing extended release matrix tablets of poorly water-soluble diclofenac sodium and highly water-soluble metformin hydrochloride by direct compression using cashew gum, xanthan gum and hydroxypropylmethylcellulose (HPMC) as release retardants. The suitability of light gra...