Identification of the BRCA1 Gene Mutations in Exons 6, 13, and 20 in Patients with Breast Cancer, South Khorasan Province, Iran

• Autors principals: Ghazaleh Khalili Tanha (Autor), Ahmadreza Sebzari (Autor), Mitra Moodi (Autor), Mohsen Naseri (Autor)
• Format: Llibre
• Publicat: Mashhad University of Medical Sciences, 2018-04-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Introduction: Breast cancer is the most prevalent malignancy among females and the first leading cause of death from cancer in women. This highly heterogeneous disease is multifactorial. Mutations in BRCA1 and BRCA2 genes, which contribute to DNA repair, are the causes of 20-30% of hereditary breast...