Neuroprotection in an Experimental Model of Multiple Sclerosis via Opening of Big Conductance, Calcium-Activated Potassium Channels

• 主要な著者: Gareth Pryce (著者), Sofia Sisay (著者), Gavin Giovannoni (著者), David L. Selwood (著者), David Baker (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2023-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Big conductance calcium-activated (BK) channel openers can inhibit pathologically driven neural hyperactivity to control symptoms via hyperpolarizing signals to limit neural excitability. We hypothesized that BK channel openers would be neuroprotective during neuroinflammatory, autoimmune disease. T...