Neuroprotection in an Experimental Model of Multiple Sclerosis via Opening of Big Conductance, Calcium-Activated Potassium Channels

Big conductance calcium-activated (BK) channel openers can inhibit pathologically driven neural hyperactivity to control symptoms via hyperpolarizing signals to limit neural excitability. We hypothesized that BK channel openers would be neuroprotective during neuroinflammatory, autoimmune disease. T...

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Main Authors: Gareth Pryce (Author), Sofia Sisay (Author), Gavin Giovannoni (Author), David L. Selwood (Author), David Baker (Author)
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Publicado em: MDPI AG, 2023-07-01T00:00:00Z.
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