Immunization of mice by a multimeric L2-based linear epitope (17-36) from HPV type 16/18 induced cross reactive neutralizing antibodies

• Main Authors: Farhad Motavalli Khiavi (Author), Arash Arashkia (Author), Maryam Nasimi (Author), Mehdi Mahdavi (Author), Majid Golkar (Author), Farzin Roohvand (Author), Kayhan Azadmanesh (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Current licensed and commercially available prophylactic human papillomavirus (HPV) vaccines (Cervarix and quadrivalent/nine valents Gardasil) are based on major capsid protein L1 virus-like particles (VLPs) production which are expensive and type specific. Minor capsid L2-RG1 linear epitope (17-36)...