Repurposing pantoprazole and haloperidol as efflux pump inhibitors in azole resistant clinical Candida albicans and non-albicans isolates

Candida species have a major role in nosocomial infections leading to high morbidity and mortality. Increased resistance to various antifungals, especially azoles is a significant problem. One of the main mechanisms for azole resistance is the up-regulation of efflux pump genes including CDR1 and MD...

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Main Authors: Amira M. El-Ganiny (Author), Hend A. Kamel (Author), Nehal E. Yossef (Author), Basem Mansour (Author), Ahmed M. El-Baz (Author)
Format: Book
Published: Elsevier, 2022-03-01T00:00:00Z.
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