Modulation of the immune response by Fonsecaea pedrosoi morphotypes in the course of experimental chromoblastomycosis and their role on inflammatory response chronicity.

• Main Authors: Isaque Medeiros Siqueira (Author), Raffael Júnio Araújo de Castro (Author), Luiza Chaves de Miranda Leonhardt (Author), Márcio Sousa Jerônimo (Author), Aluízio Carlos Soares (Author), Tainá Raiol (Author), Christiane Nishibe (Author), Nalvo Almeida (Author), Aldo Henrique Tavares (Author), Christian Hoffmann (Author), Anamelia Lorenzetti Bocca (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A common theme across multiple fungal pathogens is their ability to impair the establishment of a protective immune response. Although early inflammation is beneficial in containing the infection, an uncontrolled inflammatory response is detrimental and may eventually oppose disease eradication. Chr...