Downregulated lncRNA HOXA11-AS Affects Trophoblast Cell Proliferation and Migration by Regulating RND3 and HOXA7 Expression in PE

• Main Authors: Yetao Xu (Author), Dan Wu (Author), Jie Liu (Author), Shiyun Huang (Author), Qing Zuo (Author), Xi Xia (Author), Ying Jiang (Author), Sailan Wang (Author), Yanzi Chen (Author), Tianjun Wang (Author), Lizhou Sun (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The long noncoding RNA HOXA11-AS displays abnormal expression in numerous human diseases. However, its function and biological mechanisms remain unclear in preeclampsia (PE). In this study, we report that HOXA11-AS is significantly downregulated in preeclamptic placental tissues and could contribute...