Role of L-, N- and T-type Calcium Channels in Achieving Maximum Analgesic and Minimum Toxic Effect of Tramadol

• Main Authors: Mehmet Yilmaz (Author), Bahadir Suleyman (Author), Renad Mammadov (Author), Durdu Altuner (Author), Taha Abdulkadir Coban (Author), Seval Bulut (Author), Halis Suleyman (Author), Resid Coskun (Author)
• Format: Book
• Published: Polskie Towarzystwo Farmaceutyczne, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the study was to investigate the effects of lacidipine, amlodipine and benidipine on the analgesic activity and toxicity of tramadol. Rats (n=6/each group) were divided into five groups as control(CG), tramadol(TRD), lacidipine+tramadol(LTRD), amlodipine+tramadol(ATRD) and benidipine+tram...