MiR-145 regulates steroidogenesis in mouse primary granulosa cells by targeting Arpc5 and subsequent cytoskeleton remodeling

• Main Authors: Lanfang MA (Author), Shuo WANG (Author), Jun YANG (Author), Weicheng TANG (Author), Zhangying WU (Author), Lili CAO (Author), Aiyue LUO (Author), Fangfang FU (Author), Shuhong YANG (Author), Shixuan WANG (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MicroRNA (miR)-145 is enriched in the follicular granulosa cells (GCs) of 3-week-old mice. Downregulating miR-145 inhibits the proliferation and differentiation of GCs and induces evident changes in their cytoskeleton. In this study, we examined how miR-145 induces cytoskeletal changes in mouse GCs...