Locomotor and gait changes in the LPS model of neuroinflammation are correlated with inflammatory cytokines in blood and brain

• Main Authors: Diogo Carregosa (Author), Natasa Loncarevic-Vasiljkovic (Author), Raquel Feliciano (Author), Diogo Moura-Louro (Author), César S. Mendes (Author), Cláudia Nunes dos Santos (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Lipopolysaccharide (LPS) challenge in mice has been used to identify the mechanisms and therapeutics for neuroinflammation. In this study, we aimed to comprehensively evaluate the behavioral changes including locomotion, exploration, and memory, correlating them with a panel of thirteen inf...