Metabotropic Glutamate Receptor Subtype 5 Positron-Emission-Tomography Radioligands as a Tool for Central Nervous System Drug Development: Between Progress and Setbacks

• Main Authors: Anne-Claire Dupont (Author), Nicolas Arlicot (Author), Johnny Vercouillie (Author), Sophie Serrière (Author), Serge Maia (Author), Frédérique Bonnet-Brilhault (Author), Maria-Joao Sa (Author)
• 格式: 圖書
• 出版: MDPI AG, 2023-08-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The metabotropic glutamate receptor subtype 5 (mGluR5) is a class C G-protein-coupled receptor (GPCR) that has been implicated in various neuronal processes and, consequently, in several neuropsychiatric or neurodevelopmental disorders. Over the past few decades, mGluR5 has become a major focus for...