Deconvolution of synthetic mRNA expression: Nucleoside chemistry alters translatability
Abstract Recent technological advances in the production of in vitro transcribed messenger RNA (IVT‐mRNA) facilitate its clinical use as well as its application in basic research. In this regard, numerous chemical modifications, which are not naturally observed in endogenous mRNA, have been implemen...
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Main Authors: | Hanieh Moradian (Author), Marko Schwestka (Author), Toralf Roch (Author), Manfred Gossen (Author) |
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Format: | Book |
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Wiley,
2024-07-01T00:00:00Z.
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