Synergistic Activity and Mechanism of Sanguinarine with Polymyxin B against Gram-Negative Bacterial Infections

• Main Authors: Luyao Qiao (Author), Yu Zhang (Author), Ying Chen (Author), Xiangyin Chi (Author), Jinwen Ding (Author), Hongjuan Zhang (Author), Yanxing Han (Author), Bo Zhang (Author), Jiandong Jiang (Author), Yuan Lin (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Compounds that potentiate the activity of clinically available antibiotics provide a complementary solution, except for developing novel antibiotics for the rapid emergence of multidrug-resistant Gram-negative bacteria (GNB). We sought to identify compounds potentiating polymyxin B (PMB), a traditio...