Fatty acid amide hydrolase inhibition and N‐arachidonoylethanolamine modulation by isoflavonoids: A novel target for upcoming antidepressants

• Main Authors: Wahid Zada (Author), Jonathan W. VanRyzin (Author), Miguel Perez‐Pouchoulen (Author), Samantha L. Baglot (Author), Matthew N. Hill (Author), Ghulam Abbas (Author), Sarah M. Clark (Author), Umer Rashid (Author), Margaret M. McCarthy (Author), Abdul Mannan (Author)
• Format: Book
• Published: Wiley, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Modulation of the endocannabinoid system (ECS) is a novel putative target for therapeutic intervention in depressive disorders. Altering concentrations of one of the principal endocannabinoids, N‐arachidonoylethanolamine, also known as anandamide (AEA) can affect depressive‐like behaviors t...