Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice

• Egile Nagusiak: Liu Yen-Chin (Egilea), Berta Temugin (Egilea), Liu Tong (Egilea), Tan Ping-Heng (Egilea), Ji Ru-Rong (Egilea)
• Formatua: Liburua
• Argitaratua: SAGE Publishing, 2012-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Despite decades of intense research efforts, actions of acute opioids are not fully understood. Increasing evidence suggests that in addition to well-documented antinociceptive effects opioids also produce paradoxical hyperalgesic an...