Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans

• Үндсэн зохиолчид: Fabiana Gomes Nascimento Soares (Зохиогч), Gabriela Göethel (Зохиогч), Luciano Porto Kagami (Зохиогч), Gustavo Machado das Neves (Зохиогч), Elisa Sauer (Зохиогч), Estefania Birriel (Зохиогч), Javier Varela (Зохиогч), Itamar Luís Gonçalves (Зохиогч), Gilsane Von Poser (Зохиогч), Mercedes González (Зохиогч), Daniel Fábio Kawano (Зохиогч), Fávero Reisdorfer Paula (Зохиогч), Eduardo Borges de Melo (Зохиогч), Solange Cristina Garcia (Зохиогч), Hugo Cerecetto (Зохиогч), Vera Lucia Eifler-Lima (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2019-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background Chagas disease (CD) is a tropical parasitic disease. Although the number of people infected is very high, the only drugs available to treat CD, nifurtimox (Nfx) and benznidazole, are highly toxic, particularly in the chronic stage of the disease. Coumarins are a large class of co...