Development of a Topical Amphotericin B and <i>Bursera graveolens</i> Essential Oil-Loaded Gel for the Treatment of Dermal Candidiasis

• Main Authors: Lupe Carolina Espinoza (Author), Lilian Sosa (Author), Paulo C. Granda (Author), Nuria Bozal (Author), Natalia Díaz-Garrido (Author), Brenda Chulca-Torres (Author), Ana Cristina Calpena (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The higher molecular weight and low solubility of amphotericin B (AmB) hinders its topical administration. The aim of this study was to incorporate <i>Bursera graveolens</i> essential oil into an AmB topical gel (AmB + BGEO gel) in order to promote the diffusion of the drug through the s...