Targeting Ephrin Receptor Tyrosine Kinase A2 with a Selective Aptamer for Glioblastoma Stem Cells

• Main Authors: Alessandra Affinito (Author), Cristina Quintavalle (Author), Carla Lucia Esposito (Author), Giuseppina Roscigno (Author), Catello Giordano (Author), Silvia Nuzzo (Author), Lucia Ricci-Vitiani (Author), Iolanda Scognamiglio (Author), Zoran Minic (Author), Roberto Pallini (Author), Maxim V. Berezovski (Author), Vittorio de Francisis (Author), Gerolama Condorelli (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the benefits associated with radiotherapy and chemotherapy for glioblastoma (GBM) treatment, most patients experience a relapse following initial therapy. Recurrent or progressive GBM usually does not respond anymore to standard therapy, and this is associated with poor patient outcome. GBM...