Protective Effects of 6-Gingerol on Cardiotoxicity Induced by Arsenic Trioxide Through AMPK/SIRT1/PGC-1α Signaling Pathway

• Main Authors: Xue Han (Author), Yakun Yang (Author), Muqing Zhang (Author), Xi Chu (Author), Bin Zheng (Author), Chenxu Liu (Author), Yucong Xue (Author), Shengjiang Guan (Author), Shijiang Sun (Author), Qingzhong Jia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Objective: Arsenic trioxide (As2O3) induced cardiotoxicity to limit the clinical applications of the effective anticancer agent. 6-Gingerol (6G) is the main active ingredient of ginger, a food with many health benefits. The present study aims to investigate the potential pharmacologic...