Ketamine Alleviates Postoperative Depression-Like Symptoms in Susceptible Mice: The Role of BDNF-TrkB Signaling

• Main Authors: Shan Li (Author), Xiaoxiao Luo (Author), Dongyu Hua (Author), Yue Wang (Author), Gaofeng Zhan (Author), Niannian Huang (Author), Riyue Jiang (Author), Ling Yang (Author), Bin Zhu (Author), Xianglin Yuan (Author), Ailin Luo (Author), Chun Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Patients are more likely to suffer from central nervous system (CNS) complications after anesthesia and surgery. However, postoperative depression (POD) has not yet received sufficient attentions, and its pathogenesis and therapeutic strategies remain poorly understood. We here aimed to investigate...