New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling

• Main Authors: Mohamed A. Abdelgawad (Author), Syed N. A. Bukhari (Author), Arafa Musa (Author), Mohammed Elmowafy (Author), Mohammed H. Elkomy (Author), AbdElAziz. A. Nayl (Author), Ahmed H. El-Ghorab (Author), Ibrahim Hotan Alsohaimi (Author), Mohamed Sadek Abdel-Bakky (Author), Ibrahim O. Althobaiti (Author), Hamud A. Altaleb (Author), Hany A. Omar (Author), Ahmed H. Abdelazeem (Author), Mohamed A. Zaki (Author), Mohamed E. Shaker (Author), Heba A. H. Elshemy (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study new sulphamethoxazole derivatives (<b>S1<b>-</b>S4</b>, <b>S6<b>-</b>S12</b>, and <b>S14<b>-</b>S22</b>) were designed and synthesized and their structures were fully characterized and validated using NMR, mass, an...