Vitexicarpin inhibits overexpression of GNAO1 and plays a role in gastric cancer cell proliferation and apoptosis

• Main Authors: Si-Ping Wang (Author), Li Yu (Author), Jie Xie (Author), Xiao-Ming Liu (Author), Hong Li (Author)
• Formato: Livro
• Publicado em: Bangladesh Pharmacological Society, 2015-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The present study demonstrates the effect of vitexicarpin on down-regulation of GNAO1 in human gastric cancer cell lines. The results from Western blot analysis revealed that vitexicarpin treatment inhibited the GNAO1 expression in MKN-45 cells at a concentration of 30 µM. Examination of cell prolif...