Vitexicarpin inhibits overexpression of GNAO1 and plays a role in gastric cancer cell proliferation and apoptosis

• Главные авторы: Si-Ping Wang (Автор), Li Yu (Автор), Jie Xie (Автор), Xiao-Ming Liu (Автор), Hong Li (Автор)
• Формат: ‌
• Опубликовано: Bangladesh Pharmacological Society, 2015-01-01T00:00:00Z.
• Предметы: article
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The present study demonstrates the effect of vitexicarpin on down-regulation of GNAO1 in human gastric cancer cell lines. The results from Western blot analysis revealed that vitexicarpin treatment inhibited the GNAO1 expression in MKN-45 cells at a concentration of 30 µM. Examination of cell prolif...