New Application of the Commercially Available Dye Celestine Blue B as a Sensitive and Selective Fluorescent "Turn-On" Probe for Endogenous Detection of HOCl and Reactive Halogenated Species

• Main Authors: Veronika E. Reut (Author), Stanislav O. Kozlov (Author), Igor V. Kudryavtsev (Author), Natalya A. Grudinina (Author), Valeria A. Kostevich (Author), Nikolay P. Gorbunov (Author), Daria V. Grigorieva (Author), Julia A. Kalvinkovskaya (Author), Sergey B. Bushuk (Author), Elena Yu Varfolomeeva (Author), Natalia D. Fedorova (Author), Irina V. Gorudko (Author), Oleg M. Panasenko (Author), Vadim B. Vasilyev (Author), Alexey V. Sokolov (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypochlorous acid (HOCl) derived from hydrogen peroxide and chloride anion by myeloperoxidase (MPO) plays a significant role in physiological and pathological processes. Herein we report a phenoxazine-based fluorescent probe Celestine Blue B (CB) that is applicable for HOCl detection in living cells...