Sodium Tanshinone II-A Sulfonate (DS-201) Induces Vasorelaxation of Rat Mesenteric Arteries via Inhibition of L-Type Ca2+ Channel

• Main Authors: Xiao-Dong Zhang (Author), Chun-Xia He (Author), Jun Cheng (Author), Jing Wen (Author), Peng-Yun Li (Author), Na Wang (Author), Guang Li (Author), Xiao-Rong Zeng (Author), Ji-Min Cao (Author), Yan Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: We previously have proved that sodium tanshinone II-A sulfonate (DS-201), a derivative of traditional Chinese medicinal herb Danshen (Salvia miltiorrhiza), is an opener and vasodilator of BKCa channel in the vascular smooth muscle cells (VSMCs). Vascular tension is closely associated wit...