Histamine as a marker for hydroxyl radicals

• Main Authors: T.-L. Ching (Author), R. M. van der Hee (Author), N. M. Bhoelan (Author), J. Blauw (Author), W. M. P. B. Menge (Author), J. de Jong (Author), A. Bast (Author)
• Format: Book
• Published: Hindawi Limited, 1995-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During inflammation an influx of neutrophils and release of mediators from mast cells (such as histamine) take place. The stimulated neutrophils can produce reactive oxygen species (ROS). One of these ROS is the highly reactive hydroxyl radical (OH.). It would be interesting to be able to quantify t...