miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease

• Main Authors: Pablo Fernández-Tussy (Author), David Fernández-Ramos (Author), Fernando Lopitz-Otsoa (Author), Jorge Simón (Author), Lucía Barbier-Torres (Author), Beatriz Gomez-Santos (Author), Maitane Nuñez-Garcia (Author), Mikel Azkargorta (Author), Virginia Gutiérrez-de Juan (Author), Marina Serrano-Macia (Author), Rubén Rodríguez-Agudo (Author), Paula Iruzubieta (Author), Juan Anguita (Author), Rui E. Castro (Author), Devin Champagne (Author), Mercedes Rincón (Author), Felix Elortza (Author), Anita Arslanow (Author), Marcin Krawczyk (Author), Frank Lammert (Author), Mélanie Kirchmeyer (Author), Iris Behrmann (Author), Javier Crespo (Author), Shelly C. Lu (Author), José M. Mato (Author), Marta Varela-Rey (Author), Patricia Aspichueta (Author), Teresa C. Delgado (Author), María L. Martínez-Chantar (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Non-alcoholic fatty liver disease (NAFLD) is a complex pathology in which several dysfunctions, including alterations in metabolic pathways, mitochondrial functionality and unbalanced lipid import/export, lead to lipid accumulation and progression to inflammation and fibrosis. The enzyme...