Synchronous conjugation of i-motif DNA and therapeutic siRNA on the vertexes of tetrahedral DNA nanocages for efficient gene silence

The functionality of DNA biomacromolecules has been widely excavated, as therapeutic drugs, carriers, and functionalized modification derivatives. In this study, we developed a series of DNA tetrahedron nanocages (Td), via synchronous conjugating different numbers of i-(X) and therapeutic siRNA on f...

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Main Authors: Xiu Han (Author), Xiang Xu (Author), Ziheng Wu (Author), Zhenghong Wu (Author), Xiaole Qi (Author)
Format: Book
Published: Elsevier, 2021-10-01T00:00:00Z.
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