Link Protein N-Terminal Peptide as a Potential Stimulating Factor for Stem Cell-Based Cartilage Regeneration

• Main Authors: Ruijun He (Author), Baichuan Wang (Author), Min Cui (Author), Zekang Xiong (Author), Hui Lin (Author), Lei Zhao (Author), Zhiliang Li (Author), Zhe Wang (Author), Shaun Peggrem (Author), Zhidao Xia (Author), Zengwu Shao (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Link protein N-terminal peptide (LPP) in extracellular matrix (ECM) of cartilage could induce synthesis of proteoglycans and collagen type II in cartilaginous cells. Cartilage stem/progenitor cells (CSPCs), the endogenous stem cells in cartilage, are important in cartilage degeneration a...