Ferulic acid regulates the Nrf2/heme oxygenase-1 system and counteracts trimethyltin-induced neuronal damage in the human neuroblastoma cell line SH-SY5Y.

• Main Authors: Stefania eCatino (Author), Fabiola ePaciello (Author), Fiorella eMiceli (Author), Rolando eRolesi (Author), Diana eTroiani (Author), Vittorio eCalabrese (Author), Rosaria eSantangelo (Author), Cesare eMancuso (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Over the past years, several lines of evidence have pointed out the efficacy of ferulic acid (FA) in counteracting oxidative stress elicited by β-amyloid or free radical initiators, based on the ability of this natural antioxidant to up-regulate the heme oxygenase-1 (HO-1) and biliverdin reductase (...