Luteolin Exerts Neuroprotection via Modulation of the p62/Keap1/Nrf2 Pathway in Intracerebral Hemorrhage

• Main Authors: Xin Tan (Author), Yi Yang (Author), Jianguo Xu (Author), Peng Zhang (Author), Ruming Deng (Author), Yiguang Mao (Author), Jia He (Author), Yibin Chen (Author), Yan Zhang (Author), Jiasheng Ding (Author), Haiying Li (Author), Haitao Shen (Author), Xiang Li (Author), Wanli Dong (Author), Gang Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Upregulation of neuronal oxidative stress is involved in the progression of secondary brain injury (SBI) following intracerebral hemorrhage (ICH). In this study, we investigated the potential effects and underlying mechanisms of luteolin on ICH-induced SBI. Autologous blood and oxyhemoglobin (OxyHb)...