Carnosine Mitigates Manganese Mitotoxicity in an In Vitro Model of Isolated Brain Mitochondria

• Main Authors: Vahid Ghanbarinejad (Author), Asrin Ahmadi (Author), Hossein Niknahad (Author), Mohammad Mehdi Ommati (Author), Reza Heidari (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Manganese (Mn) is a neurotoxic chemical which induces a wide range of complications in the brain tissue. Impaired locomotor activity and cognitive dysfunction are associated with high brain Mn content. At the cellular level, mitochondria are potential targets for Mn toxicity. Carnosine is a...