A novel and selective fluorescent ligand for the study of adenosine A2B receptors

• Main Authors: Foteini Patera (Author), Sarah J. Mistry (Author), Nicholas D. Kindon (Author), Eleonora Comeo (Author), Joelle Goulding (Author), Barrie Kellam (Author), Laura E. Kilpatrick (Author), Hester Franks (Author), Stephen J. Hill (Author)
• Format: Book
• Published: Wiley, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Fluorescent ligands have proved to be powerful tools in the study of G protein‐coupled receptors in living cells. Here we have characterized a new fluorescent ligand PSB603‐BY630 that has high selectivity for the human adenosine A2B receptor (A2BR). The A2BR appears to play an important rol...