Effect of heme oxygenase-1 polymorphisms on lung function and gene expression

• Main Authors: Abboud Raja T (Author), Anthonisen Nicholas R (Author), Connett John E (Author), Shumansky Karey (Author), He Jian-Qing (Author), Akhabir Loubna (Author), Aminuddin Farzian (Author), Tanaka Goh (Author), Paré Peter D (Author), Sandford Andrew J (Author)
• Format: Book
• Published: BMC, 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Oxidative stress induced by smoking is considered to be important in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Heme oxygenase-1 (HMOX1) is an essential enzyme in heme catabolism that is induced by oxidative st...