A molecular network-based pharmacological study on the protective effect of Panax notoginseng rhizomes against renal ischemia-reperfusion injury

• Main Authors: Dan-Dan Li (Author), Na Li (Author), Chui Cai (Author), Chun-Mian Wei (Author), Guang-Hua Liu (Author), Ting-Hua Wang (Author), Fu-Rong Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: We aimed to explore the protective effect of Panax notoginseng rhizomes (PNR) on renal ischemia and reperfusion injury (RIRI) and the underlying molecular network mechanism based on network pharmacology and combined systemic experimental validation.Methods: A bilateral RIRI model was esta...