Rapid and scalable plant-based production of a cholera toxin B subunit variant to aid in mass vaccination against cholera outbreaks.

• Главные авторы: Krystal Teasley Hamorsky (Автор), J Calvin Kouokam (Автор), Lauren J Bennett (Автор), Keegan J Baldauf (Автор), Hiroyuki Kajiura (Автор), Kazuhito Fujiyama (Автор), Nobuyuki Matoba (Автор)
• Формат: ‌
• Опубликовано: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Предметы: article
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INTRODUCTION: Cholera toxin B subunit (CTB) is a component of an internationally licensed oral cholera vaccine. The protein induces neutralizing antibodies against the holotoxin, the virulence factor responsible for severe diarrhea. A field clinical trial has suggested that the addition of CTB to ki...