Intraperitoneal injection of thalidomide attenuates bone cancer pain and decreases spinal tumor necrosis factor-α expression in a mouse model

• Main Authors: Zhang Juan (Author), Mei Fengmei (Author), Zhang Rui (Author), Ren Bingxu (Author), Zheng Yaguo (Author), Gu Xiaoping (Author), Ma Zhengliang (Author)
• Format: Book
• Published: SAGE Publishing, 2010-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Tumor necrosis factor α (TNF-α) may have a pivotal role in the genesis of mechanical allodynia and thermal hyperalgesia during inflammatory and neuropathic pain. Thalidomide has been shown to selectively inhibit TNF-α production. Pre...