Clinically important change for the FACIT-Fatigue scale in paroxysmal nocturnal hemoglobinuria: a derivation from international PNH registry patient data

• Main Authors: David Cella (Author), Peter Johansson (Author), Yasutaka Ueda (Author), Ioannis Tomazos (Author), Philippe Gustovic (Author), Alice Wang (Author), Ami S. Patel (Author), Hubert Schrezenmeier (Author)
• Format: Book
• Published: SpringerOpen, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Fatigue is the most common symptom associated with paroxysmal nocturnal hemoglobinuria (PNH). The objective of this analysis was to estimate values that would suggest a clinically important change (CIC) for the functional assessment of chronic illness therapy-fatigue scale (FACIT...