Twin Screw Melt Granulation: A Single Step Approach for Developing Self-Emulsifying Drug Delivery System for Lipophilic Drugs

• Main Authors: Dinesh Nyavanandi (Author), Preethi Mandati (Author), Sagar Narala (Author), Abdullah Alzahrani (Author), Praveen Kolimi (Author), Sateesh Kumar Vemula (Author), Michael A. Repka (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The current research aims to improve the solubility of the poorly soluble drug, i.e., ibuprofen, by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt granulation (TSMG) approach. Gelucire^® 44/14, Gelucire^® 48/16, and T...