Twin Screw Melt Granulation: A Single Step Approach for Developing Self-Emulsifying Drug Delivery System for Lipophilic Drugs

• Autors principals: Dinesh Nyavanandi (Autor), Preethi Mandati (Autor), Sagar Narala (Autor), Abdullah Alzahrani (Autor), Praveen Kolimi (Autor), Sateesh Kumar Vemula (Autor), Michael A. Repka (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2023-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The current research aims to improve the solubility of the poorly soluble drug, i.e., ibuprofen, by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt granulation (TSMG) approach. Gelucire^® 44/14, Gelucire^® 48/16, and T...