Small animal PET imaging with the 68Ga-labeled pH (low) insertion peptide-like peptide YJL-4 in a triple-negative breast cancer mouse model

• Main Authors: YueHua Chen (Author), ShuangShuang Song (Author), YanQin Sun (Author), FengYu Wu (Author), GuangJie Yang (Author), ZhenGuang Wang (Author), MingMing Yu (Author)
• Format: Book
• Published: SpringerOpen, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The aim of this study was to prepare a novel 68Ga-labeled pH (low) insertion peptide (pHLIP)-like peptide, YJL-4, and determine its value for the early diagnosis of triple-negative breast cancer (TNBC) via in vivo imaging of tumor-bearing nude mice. The novel peptide YJL-4 was de...