Positron Emission Tomography (PET) and Pharmacokinetics: Classical Blood Sampling Versus Image-Derived Analysis of [18F]FAZA and [18F]FDG in a Murine Tumor Bearing Model

• Asıl Yazarlar: Hans-Soenke Jans (Yazar), Xiao-Hong Yang (Yazar), Dion R Brocks (Yazar), Piyush Kumar (Yazar), Melinda Wuest (Yazar), Leonard I Wiebe (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2018-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Purpose: Pharmacokinetic (PK) data are generally derived from blood samples withdrawn serially over a defined period after dosing. In small animals, blood sampling after dosing presents technical difficulties, particularly when short time intervals and frequent sampling are required. Positron emissi...