Cardioprotective Effect of Rheum turkestanicum Against Doxorubicin-Induced Toxicity in Rats

• Main Authors: Azar Hosseini (Author), Mohammad-Kazem Safari (Author), Arezoo Rajabian (Author), Samaneh Boroumand-Noughabi (Author), Ali H. Eid (Author), Yusra Al Dhaheri (Author), Eric Gumpricht (Author), Amirhossein Sahebkar (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum turkestanicum (R.turkestanicum) extract against doxorubicin cardiotoxicity due...