2-Deoxy-D-glucose and combined 2-Deoxy-D-glucose/albendazole exhibit therapeutic efficacy against Echinococcus granulosus protoscoleces and experimental alveolar echinococcosis.

• Main Authors: Qi Xin (Author), Wei Lv (Author), Yunxi Xu (Author), Yumei Luo (Author), Caifang Zhao (Author), Bichen Wang (Author), Miaomiao Yuan (Author), Huanping Li (Author), Xiaoxia Song (Author), Tao Jing (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

2-Deoxy-D-glucose (2-DG) is a glucose analog used as a promising anticancer agent. It exerts its effects by inhibiting the glycolytic energy metabolism to deplete cells of energy. The larval stage of Echinococcus relies on glycolysis for energy production. Therefore, in this study, we investigated t...