The effects of apixaban on clot characteristics in atrial fibrillation: A novel pharmacodynamic biomarker

• Main Authors: Matthew J. Lawrence (Author), Vanessa Evans (Author), Janet Whitley (Author), Suresh Pillai (Author), Phylip R. Williams (Author), James Coulson (Author), Manju Krishnan (Author), Peter Slade (Author), Kieron Power (Author), Roger H.K. Morris (Author), Phillip A. Evans (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Atrial fibrillation (AF) is a major risk factor for stroke. We aim to characterize AF patients and the effects of apixaban therapy in terms of clot microstructure using gel point analysis, a novel biomarker. Seventy‐eight patients were included in the study, 50 Stroke with AF (AF‐S), and 28...