Evaluation of Chikungunya diagnostic assays: differences in sensitivity of serology assays in two independent outbreaks.

• Main Authors: Grace Yap (Author), Kwoon-Yong Pok (Author), Yee-Ling Lai (Author), Hapuarachchige-Chanditha Hapuarachchi (Author), Angela Chow (Author), Yee-Sin Leo (Author), Li-Kiang Tan (Author), Lee-Ching Ng (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: The sensitivity and specificity of two in-house MAC-ELISA assays were tested and compared with the performance of commercially-available CTK lateral flow rapid test and EUROIMMUN IFA assays for the detection of anti-Chikungunya virus (CHIKV) IgM. Each MAC-ELISA assay used a whole virus-b...