Pharmacokinetics of immediate and sustained-release formulations of paroxetine: Population pharmacokinetic approach to guide paroxetine personalized therapy in chinese psychotic patients

• Main Authors: Xiao-lin Li (Author), Shan-qing Huang (Author), Tao Xiao (Author), Xi-pei Wang (Author), Wan Kong (Author), Shu-jing Liu (Author), Zi Zhang (Author), Ye Yang (Author), Shan-shan Huang (Author), Xiao-jia Ni (Author), Hao-yang Lu (Author), Ming Zhang (Author), Yu-guan Wen (Author), De-wei Shang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Paroxetine is one of the most potent selective serotonin reuptake inhibitors (SSRIs) approved for treating depression, panic disorder, and obsessive-compulsive disorder. There is evidence linking genetic polymorphisms and nonlinear metabolism to the Paroxetine's pharmacokinetic (PK) variability...