Syntheses and evaluation of multicaulin and miltirone-like compounds as antituberculosis agents

• Main Authors: Serdar Burmaoğlu (Author), Hatice Seçinti (Author), Erkan Mozioğlu (Author), Ahmet C. Gören (Author), Ramazan Altundaş (Author), Hasan Seçen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Four multicaulin and miltirone-like phenanthrene derivatives were synthesised and evaluated as antituberculosis agents. The crucial step of the synthesis was Pschorr coupling of 4-(3-isopropyl-4-methoxyphenyl)-2-(2-aminophenyl)ethane (13) to give 2-isopropyl-3-methoxy-9,10-dihydrophenanthrene (9) an...