Immune evasion and recognition of the syphilis spirochete in blood and skin of secondary syphilis patients: two immunologically distinct compartments.

• Main Authors: Adriana R Cruz (Author), Lady G Ramirez (Author), Ana V Zuluaga (Author), Allan Pillay (Author), Christine Abreu (Author), Carlos A Valencia (Author), Carson La Vake (Author), Jorge L Cervantes (Author), Star Dunham-Ems (Author), Richard Cartun (Author), Domenico Mavilio (Author), Justin D Radolf (Author), Juan C Salazar (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The clinical syndrome associated with secondary syphilis (SS) reflects the propensity of Treponema pallidum (Tp) to escape immune recognition while simultaneously inducing inflammation. METHODS:To better understand the duality of immune evasion and immune recognition in human syphilis, he...