Pharmacodynamic Evaluation of Shenfu Injection in Rats With Ischemic Heart Failure and Its Effect on Small Molecules Using Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging

• Autori principali: Hao Wu (Autore), Zhenfeng Dai (Autore), Xi Liu (Autore), Ming Lin (Autore), Zeyu Gao (Autore), Fang Tian (Autore), Xin Zhao (Autore), Yi Sun (Autore), Xiaoping Pu (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Objectives: We aimed to evaluate the effect of Shenfu injection in a rat model of ischemic heart failure and explore its mechanism.Methods: A rat model of ischemic heart failure after myocardial infarction was established by ligating the left anterior descending coronary artery. Forty-eight hours af...